Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.47 |
| ▸ | HTR1D | P28221 | 9/20 | 0.47 |
| ▸ | HTR1B | P28222 | 9/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306763 | 0.79 | HTR1A (0.57) | HTR1AHTR1DHTR1BTSHRWDR5 | |
| SCHEMBL6306090 | 0.79 | HTR1A (0.58) | HTR1AHTR1DHTR1BHTR2CSLC6A9 | |
| SCHEMBL8567402 | 0.79 | HTR1A (0.50) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL8572292 | 0.78 | HRH3 (0.50) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL7812700 | 0.75 | HTR1A (0.57) | HTR1AHTR1DHTR1BTSHRALDH1A1 | |
| SCHEMBL6308232 | 0.75 | RAB9A (0.55) | HTR1AHTR1DHTR1BLMNAMAPT | |
| SCHEMBL6308076 | 0.75 | KMT2A (0.53) | HTR1AHTR1DHTR1BALDH1A1LMNA | |
| SCHEMBL7812213 | 0.74 | KDM4E (0.60) | HTR1AHTR1DHTR1BTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL6306223 | 0.74 | HTR1A (0.56) | HTR1AHTR1DHTR1BTSHRALDH1A1 | |
| SCHEMBL7809208 | 0.73 | HTR1A (0.53) | HTR1AHTR1DHTR1BHTR2CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821245-A | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1998-10-13 | — | — | US | disclosed |