Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.50 |
| ▸ | HTR1D | P28221 | 10/20 | 0.50 |
| ▸ | HTR1B | P28222 | 10/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572292 | 0.94 | HRH3 (0.50) | HTR1AHTR1DHTR1BHRH3DRD3 | |
| SCHEMBL7809208 | 0.81 | HTR1A (0.53) | HTR1AHTR1DHTR1BHRH3DRD3 | |
| SCHEMBL6308076 | 0.80 | KMT2A (0.53) | HTR1AHTR1DHTR1BDRD3NPBWR1 | |
| SCHEMBL8570475 | 0.79 | HTR1A (0.47) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL6306763 | 0.79 | HTR1A (0.57) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL6306090 | 0.79 | HTR1A (0.58) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL7812700 | 0.75 | HTR1A (0.57) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL6308232 | 0.74 | RAB9A (0.55) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL6313105 | 0.74 | HTR1A (0.70) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL7838686 | 0.74 | HTR1A (0.55) | HTR1AHTR1DHTR1BSLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821245-A | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1998-10-13 | — | — | US | disclosed |