Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | FABP3 | P05413 | 3/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14052868 | 0.90 | FABP4 (0.56) | MEN1KMT2ASMN1; SMN2KEAP1FABP3 | |
| SCHEMBL8567749 | 0.82 | SMN1; SMN2 (0.54) | MEN1KMT2ASMN1; SMN2KEAP1L3MBTL1 | |
| SCHEMBL7855358 | 0.81 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2KEAP1FABP3 | |
| SCHEMBL8569633 | 0.81 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2KEAP1NPC1 | |
| SCHEMBL7454506 | 0.81 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2KEAP1HTT | |
| SCHEMBL14052509 | 0.81 | SMN1; SMN2 (0.54) | MEN1KMT2ASMN1; SMN2KEAP1FABP3 | |
| SCHEMBL7445918 | 0.78 | MEN1 (0.86) | MEN1KMT2ASMN1; SMN2KEAP1FABP3 | |
| SCHEMBL6677412 | 0.78 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2KEAP1FABP3 | |
| SCHEMBL30463435 | 0.78 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2KEAP1FABP3 | |
| SCHEMBL2541558 | 0.78 | CTSD (0.55) | MEN1KMT2ASMN1; SMN2KEAP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |