Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571816 | 0.87 | EPHX2 (0.40) | P2RX7CNR2ALDH1A1LMNAEPHX2 | |
| SCHEMBL8695608 | 0.73 | ALDH1A1 (0.47) | P2RX7CNR2ALDH1A1EPHX2HIF1A | |
| SCHEMBL8570979 | 0.73 | EPHX2 (0.40) | P2RX7CNR2ALDH1A1LMNAEPHX2 | |
| SCHEMBL8693041 | 0.70 | ALDH1A1 (0.45) | P2RX7NPC1RAB9ACNR2ALDH1A1 | |
| SCHEMBL8694978 | 0.69 | EPHX2 (0.46) | P2RX7NPC1MAPTRAB9ACNR2 | |
| SCHEMBL8692193 | 0.69 | EPHX2 (0.41) | P2RX7CNR2ALDH1A1LMNAEPHX2 | |
| SCHEMBL14786695 | 0.68 | MAPT (0.58) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL9091409 | 0.67 | RARA (0.43) | PPARGMAPTCNR2GAAHPGD | |
| SCHEMBL8691239 | 0.65 | EPHX2 (0.39) | P2RX7CNR2ALDH1A1LMNAEPHX2 | |
| SCHEMBL8691343 | 0.65 | EPHX2 (0.46) | P2RX7NPC1MAPTRAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |