Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691239 | 0.91 | EPHX2 (0.39) | EPHX2P2RX2CNR2ALDH1A1MEN1 | |
| SCHEMBL8695608 | 0.84 | ALDH1A1 (0.47) | EPHX2P2RX2CNR2ALDH1A1MEN1 | |
| SCHEMBL8694978 | 0.82 | EPHX2 (0.46) | EPHX2P2RX2CNR2ALDH1A1MEN1 | |
| SCHEMBL8693041 | 0.74 | ALDH1A1 (0.45) | EPHX2CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL8691343 | 0.74 | EPHX2 (0.46) | EPHX2P2RX2CNR2ALDH1A1MEN1 | |
| SCHEMBL8570549 | 0.69 | PPARG (0.45) | EPHX2CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6084415 | 0.67 | P2RX7 (0.51) | EPHX2P2RX2CNR2ALDH1A1MEN1 | |
| SCHEMBL8692195 | 0.67 | KMT2A (0.45) | CNR2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8571816 | 0.66 | EPHX2 (0.40) | EPHX2P2RX2CNR2ALDH1A1KMT2A | |
| SCHEMBL8693779 | 0.65 | CNR2 (0.45) | CNR2ALDH1A1MEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786379-A | Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-07-28 | — | — | US | disclosed |