SCHEMBL8570896

SCHEMBL8570896

CN(C)CCc1cc2ccccc2[nH]1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.55
MTNR1A P48039 1/20 0.53
MTNR1B P49286 1/20 0.53
HRH3 Q9Y5N1 3/20 0.51
HTR2C P28335 1/20 0.49
CHRNA7 P36544 1/20 0.49
HRH4 Q9H3N8 1/20 0.46
HTR6 P50406 1/20 0.46
BCHE P06276 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31059889 0.82 LOXL2 (0.69) LOXL2MTNR1AMTNR1BHRH3CHRNA7
SCHEMBL7169246 0.82 LOXL2 (0.69) LOXL2MTNR1AMTNR1BHRH3CHRNA7
SCHEMBL4728647 0.81 LOXL2 (0.58) LOXL2MTNR1AMTNR1BHRH3HRH4
SCHEMBL29750394 0.81 LOXL2 (0.58) LOXL2MTNR1AMTNR1BHRH3HRH4
SCHEMBL7067817 0.81 LOXL2 (0.50) LOXL2MTNR1AMTNR1BHRH3HTR2C
SCHEMBL28335219 0.81 LOXL2 (0.67) LOXL2MTNR1AMTNR1BHRH3CHRNA7
SCHEMBL73259 0.79 LOXL2 (0.60) LOXL2MTNR1AMTNR1BHRH3CHRNA7
SCHEMBL30610463 0.79 LOXL2 (0.60) LOXL2MTNR1AMTNR1BHRH3CHRNA7
SCHEMBL6860219 0.79 LOXL2 (0.64) LOXL2MTNR1AMTNR1BHRH3CHRNA7
SCHEMBL2512196 0.79 MTNR1A (0.65) LOXL2MTNR1AMTNR1BHRH3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5721267-A ANTICANCER AGENTS SYNTEX (U.S.A.) INC. (US) 1998-02-24 US disclosed