SCHEMBL8570991

SCHEMBL8570991

C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](CN)C(=O)OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
ATM Q13315 1/20 0.41
BTN3A1 O00481 1/20 0.40
POLB P06746 1/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SLC15A1 P46059 1/20 0.37
ELANE P08246 1/20 0.37
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9227155 0.85 SLC15A1 (0.43) ALDH1A1ATMBTN3A1POLBKMT2A
SCHEMBL9225932 0.85 SLC15A1 (0.43) ALDH1A1ATMBTN3A1POLBKMT2A
SCHEMBL8569288 0.81 MAPK1 (0.45) ALDH1A1BTN3A1KMT2AMEN1MAPK1
SCHEMBL14284307 0.79 ALDH1A1 (0.40) ALDH1A1ATMBTN3A1POLBKMT2A
SCHEMBL9314368 0.78 CPB2 (0.33) ALDH1A1POLBHPGD
SCHEMBL9805700 0.78 CPB2 (0.33) ALDH1A1POLBHPGD
SCHEMBL8573838 0.77 MEN1 (0.34) KMT2AMEN1
SCHEMBL9386301 0.77 ALDH1A1 (0.51) ALDH1A1ATMKMT2ACA12CA1
SCHEMBL8428511 0.76 SLC1A3 (0.32)
SCHEMBL25693847 0.76 ATM (0.51) ATMKMT2AMEN1CA2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5831091-A Process for preparing acetoxyazetidinone derivative and intermediate thereof TANABE SEIYAKU CO., LTD. (JP) 1998-11-03 US disclosed
EP-0774463-A1 Process for preparing acetoxyazetidinone derivative and intermediates thereof TANABE SEIYAKU CO., LTD. (JP) 1997-05-21 EP disclosed