Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571115 | 0.78 | PDE4D (0.53) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL22897264 | 0.74 | HTT (0.60) | GPBAR1HTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8573160 | 0.73 | MEN1 (0.47) | GPBAR1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8568969 | 0.72 | TACR1 (0.40) | GPBAR1TACR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30684467 | 0.71 | HTT (0.53) | HTTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL8570467 | 0.69 | L3MBTL1 (0.49) | HTTTACR1CYP2C19MEN1KMT2A | |
| SCHEMBL5883327 | 0.69 | TACR1 (0.54) | GPBAR1TACR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7452209 | 0.69 | TACR1 (0.46) | GPBAR1TACR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13325635 | 0.68 | IDO1 (0.44) | HTTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8574900 | 0.68 | TACR1 (0.42) | GPBAR1HTTTACR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |