Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | EEF2K | O00418 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193227 | 0.88 | CA1 (0.41) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL9193214 | 0.80 | ESR1 (0.39) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL8576906 | 0.79 | ESR1 (0.38) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL8574791 | 0.77 | MEN1 (0.44) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL8575917 | 0.76 | GABRA1 (0.39) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL5692047 | 0.75 | ALOX15 (0.55) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL9194772 | 0.74 | AR (0.38) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL8573280 | 0.73 | DHFR (0.35) | ESR1ESR2PTGS1ALOX5MAOA | |
| SCHEMBL10888518 | 0.72 | CA1 (0.52) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL3650882 | 0.71 | CA1 (0.41) | CA1CA2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |