Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561030 | 0.83 | POLB (0.55) | POLBSMN1; SMN2ALDH1A1MEN1CYP1A2 | |
| SCHEMBL6789754 | 0.82 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL11453214 | 0.81 | HPGD (0.55) | POLBSMN1; SMN2ALDH1A1MEN1CYP1A2 | |
| SCHEMBL10725421 | 0.81 | L3MBTL1 (0.59) | SMN1; SMN2ALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL10560652 | 0.80 | NPSR1 (0.67) | POLBSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL20083679 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL7339189 | 0.79 | POLB (0.59) | POLBSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL1011103 | 0.77 | ALDH1A1 (0.68) | POLBSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14594063 | 0.77 | KMT2A (0.60) | POLBSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8008629 | 0.77 | POLB (0.64) | POLBSMN1; SMN2ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831091-A | Process for preparing acetoxyazetidinone derivative and intermediate thereof | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0774463-A1 | Process for preparing acetoxyazetidinone derivative and intermediates thereof | TANABE SEIYAKU CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |