Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981993 | 0.78 | HDAC3 (0.64) | — | |
| SCHEMBL11388585 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL4409652 | 0.77 | POLB (0.63) | POLBALDH1A1MAPTTDP1TSHR | |
| SCHEMBL9191952 | 0.77 | HDAC3 (0.71) | MEN1KMT2AGAA | |
| SCHEMBL8575004 | 0.77 | POLB (0.56) | POLBALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL8011663 | 0.77 | ACHE (0.51) | POLBMAPTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5854957 | 0.76 | HDAC8 (0.56) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL5854988 | 0.76 | HDAC8 (0.56) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL23080107 | 0.76 | NPC1 (0.59) | — | |
| SCHEMBL6763786 | 0.76 | HDAC3 (0.74) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6056939-A | Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals | BRACCO IMAGING S.P.A. (IT) | 2000-05-02 | — | — | US | disclosed |