Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194869 | 0.89 | CA1 (0.47) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL9190461 | 0.82 | CA1 (0.44) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL27565810 | 0.81 | HSP90AA1 (0.39) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL8580208 | 0.79 | GABRA1 (0.42) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL9187827 | 0.77 | CA1 (0.39) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL11673781 | 0.76 | CA1 (0.48) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL8573268 | 0.75 | CA1 (0.41) | CA1CA2MAPTLMNACYP1A2 | |
| SCHEMBL10997298 | 0.73 | CA1 (0.61) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL9701896 | 0.73 | CA1 (0.61) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL201770 | 0.73 | CA1 (0.45) | CA1CA2GABRA1GABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |