Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497913 | 0.86 | GABRA1 (0.39) | GABRA1GABRB1GABRB2TSHRPTGS1 | |
| SCHEMBL8574791 | 0.80 | MEN1 (0.44) | LMNAHTTCA1CA2PTGS1 | |
| SCHEMBL9194869 | 0.79 | CA1 (0.47) | GABRA1GABRB1LMNAGAAGABRB2 | |
| SCHEMBL8575083 | 0.79 | CA1 (0.47) | GABRA1GABRB1LMNAGAAGABRB2 | |
| SCHEMBL8578127 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2MEN1ALDH1A1HSP90AA1 | |
| SCHEMBL7520561 | 0.77 | HSP90AA1 (0.37) | GABRA1GABRB1LMNAGAAHTT | |
| SCHEMBL5692124 | 0.77 | HPN (0.45) | LMNAGAACA1CA2CYP1A2 | |
| SCHEMBL8573273 | 0.75 | ALOX5 (0.35) | GABRA1GABRB2ALOX5MAPT | |
| SCHEMBL5692015 | 0.75 | GABRA1 (0.49) | GABRA1GABRB1LMNAGAAHTT | |
| SCHEMBL8442757 | 0.74 | ESR1 (0.50) | CA1CA2CYP3A4ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |