SCHEMBL8575329

SCHEMBL8575329

CCc1cc([S+](C)C)cc(C)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.37
ESR1 P03372 3/20 0.36
ESR2 Q92731 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MAOA P21397 2/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HMGB1 P09429 1/20 0.32
CXCL12 P48061 1/20 0.32
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6233426 0.82 SHBG (0.36) SHBGESR1ESR2GABRA1GABRB2
SCHEMBL757657 0.80 CA1 (0.52) ESR1ESR2CA1CA2ALOX5
Hydrochloric Acid SCHEMBL3646825 0.78 CA1 (0.50) ESR1ESR2CA1CA2ALOX5
SCHEMBL30576381 0.74 ALDH1A1 (0.48) SHBGESR1ESR2GABRA1GABRB2
SCHEMBL30250589 0.74 CA1 (0.59) SHBGESR1ESR2GABRA1GABRB2
SCHEMBL1021767 0.74 ALDH1A1 (0.48) SHBGESR1ESR2GABRA1GABRB2
SCHEMBL9749694 0.74 CA1 (0.59) SHBGESR1ESR2GABRA1GABRB2
SCHEMBL70083 0.74 CYP3A4 (0.42) SHBGESR1ESR2GABRA1GABRB2
SCHEMBL31028130 0.74 CA1 (0.59) SHBGESR1ESR2GABRA1GABRB2
SCHEMBL27647441 0.73 ESR1 (0.44) SHBGESR1ESR2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5783354-A QUATERNARY AMMONIUM COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-07-21 US disclosed