Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574158 | 0.89 | CPA1 (0.44) | ALDH1A1ABL1RAD52RIN1GAA | |
| SCHEMBL2524514 | 0.84 | TSHR (0.39) | MEN1KMT2APOLBSMN1; SMN2TAAR1 | |
| SCHEMBL8571587 | 0.83 | GAA (0.39) | POLBSMN1; SMN2LMNAALDH1A1PDE4A | |
| SCHEMBL8569979 | 0.83 | SMN1; SMN2 (0.41) | KMT2APOLBSMN1; SMN2MAPTLMNA | |
| SCHEMBL8572893 | 0.80 | LDHA (0.46) | POLBALDH1A1 | |
| SCHEMBL8575109 | 0.79 | MMP1 (0.39) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8571555 | 0.79 | BRD4 (0.37) | MAPTLMNAALDH1A1ABL1RAD52 | |
| SCHEMBL8575388 | 0.78 | PTGS1 (0.44) | KMT2AALDH1A1ABL1RAD52RIN1 | |
| SCHEMBL8571045 | 0.78 | ABL1 (0.42) | MEN1KMT2ANPSR1POLBMAPT | |
| SCHEMBL8574601 | 0.77 | CTSA (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |