Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 7/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 7/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322930 | 0.81 | PDK1 (0.60) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL27587770 | 0.80 | PDK1 (0.63) | PDK1PDK2PDK3PDK4MMP8 | |
| SCHEMBL11874543 | 0.78 | PDK1 (0.57) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL383023 | 0.77 | HTT (0.66) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL18638471 | 0.75 | PDK1 (0.56) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL16212234 | 0.75 | PDK1 (0.70) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL12890688 | 0.74 | PDK1 (0.51) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL11875203 | 0.74 | PDK1 (0.51) | PDK1PDK2PDK3PDK4MMP8 | |
| SCHEMBL9614330 | 0.72 | HTT (0.58) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL9709058 | 0.72 | PDK1 (0.71) | PDK1PDK2PDK3PDK4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789419-A | CARDIOVASCULAR AND BRONCHIAL DISORDERS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |