Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.70 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.70 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.70 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.54 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.54 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.54 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709058 | 0.84 | PDK1 (0.71) | PDK1PDK2PDK3PDK4HDAC3 | |
| SCHEMBL14849461 | 0.83 | PDK1 (0.63) | PDK1PDK2PDK3PDK4HDAC3 | |
| SCHEMBL474941 | 0.83 | HDAC1 (0.65) | PDK1PDK2PDK3PDK4HDAC3 | |
| SCHEMBL83110 | 0.83 | L3MBTL1 (0.78) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL28050469 | 0.82 | PDK1 (1.00) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL6359557 | 0.82 | PDK1 (1.00) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL436619 | 0.81 | PDK1 (0.61) | PDK1PDK2PDK3PDK4HDAC3 | |
| SCHEMBL3129785 | 0.81 | PDK1 (0.67) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL9677254 | 0.81 | PDK1 (0.61) | PDK1PDK2PDK3PDK4HDAC3 | |
| SCHEMBL8321463 | 0.80 | PDK1 (0.61) | PDK1PDK2PDK3PDK4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180305299-A1 | N-(2-FLUORO-2-PHENETHYL)CARBOXAMIDES AS NEMATICIDES AND ENDOPARASITICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| WO-2016066636-A1 | N-(2-HALOGEN-2-PHENETHYL)CARBOXAMIDES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-06 | — | — | WO | disclosed |
| US-20160075637-A1 | N-(2-FLUORO-2-PHENETHYL)CARBOXAMIDES AS NEMATICIDES AND ENDOPARASITICIDES | BAYER CROPSCIENCE AKTIENGESSELLSCHAFT (DE) | 2016-03-17 | — | — | US | disclosed |
| EP-2991485-A1 | N-(2-FLUORO-2-PHENETHYL)CARBOXAMIDES AS NEMATICIDES AND ENDOPARASITICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177582-A1 | N-(2-FLUORO-2-PHENETHYL)CARBOXAMIDES AS NEMATICIDES AND ENDOPARASITICIDES | BAYER CROPSCIENCE AG (DE) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305299-A1 | N-(2-FLUORO-2-PHENETHYL)CARBOXAMIDES AS NEMATICIDES AND ENDOPARASITICIDES | NIT2, PFAS, DNPH1 | PDK1 4855/4885PDK2 3875/4885PDK3 4670/4885 |
| US-20160075637-A1 | N-(2-FLUORO-2-PHENETHYL)CARBOXAMIDES AS NEMATICIDES AND ENDOPARASITICIDES | NIT2, PFAS, DNPH1 | PDK1 4855/4885PDK2 3875/4885PDK3 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.