Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584067 | 0.84 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL6096881 | 0.84 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL8572187 | 0.79 | MT-CO2 (0.54) | MT-CO2ALOX5ALDH1A1GAACYP1A2 | |
| SCHEMBL22426223 | 0.76 | ALDH1A1 (0.60) | MT-CO2ALOX5ALDH1A1GAACYP1A2 | |
| SCHEMBL5179725 | 0.76 | ALDH1A1 (0.60) | MT-CO2ALOX5ALDH1A1GAACYP1A2 | |
| SCHEMBL5180380 | 0.76 | ALDH1A1 (0.60) | MT-CO2ALOX5ALDH1A1GAACYP1A2 | |
| SCHEMBL20799611 | 0.76 | FUCA1 (0.53) | GAAHPGDTSHRDRD2DRD3 | |
| SCHEMBL17474627 | 0.76 | FUCA1 (0.53) | GAAHPGDTSHRDRD2DRD3 | |
| SCHEMBL18076673 | 0.75 | GRIN2B (0.48) | DRD2DRD3 | |
| SCHEMBL8573002 | 0.75 | DRD2 (0.47) | GAADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |