Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLD2 | O14939 | 4/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413814 | 0.90 | HRH3 (0.46) | HDAC2HDAC8HDAC6RAB9AKMT2A | |
| SCHEMBL8415393 | 0.89 | DPP4 (0.40) | LMNAOPRM1OPRD1DPP4RAB9A | |
| SCHEMBL8575558 | 0.83 | LMNA (0.37) | LMNAOPRM1OPRD1RAB9AKMT2A | |
| SCHEMBL8417066 | 0.78 | ITGB3 (0.48) | RAB9AKMT2AHRH3 | |
| SCHEMBL7275623 | 0.74 | HDAC8 (0.41) | LMNAOPRM1OPRD1HDAC2HDAC8 | |
| SCHEMBL8575284 | 0.73 | HRH3 (0.41) | SMN1; SMN2HRH3ALDH1A1 | |
| SCHEMBL8413812 | 0.72 | KDM4E (0.39) | LMNAHRH3KDM4EALDH1A1 | |
| SCHEMBL2645739 | 0.68 | GCGR (0.55) | — | |
| SCHEMBL9254174 | 0.67 | HDAC6 (0.40) | LMNAOPRM1OPRD1HDAC2HDAC8 | |
| SCHEMBL18211273 | 0.66 | NPC1 (0.46) | LMNAOPRM1OPRD1DPP4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |