Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 8/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575573 | 0.80 | PPARG (0.39) | ERBB2KDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL8575556 | 0.80 | PPARG (0.39) | ERBB2KDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL5759910 | 0.78 | FFAR1 (0.43) | ERBB2FFAR1KDM4EHPGDL3MBTL1 | |
| SCHEMBL5759912 | 0.78 | FFAR1 (0.43) | ERBB2FFAR1KDM4EHPGDL3MBTL1 | |
| SCHEMBL5758996 | 0.75 | CYP4F2 (0.42) | KDM4EALDH1A1HPGDADORA3MAPT | |
| SCHEMBL5758992 | 0.75 | CYP4F2 (0.42) | KDM4EALDH1A1HPGDADORA3MAPT | |
| SCHEMBL5758262 | 0.72 | ERBB2 (0.39) | ERBB2KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5758259 | 0.72 | ERBB2 (0.39) | ERBB2KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL14523934 | 0.70 | ERBB2 (0.50) | ERBB2MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL7959564 | 0.69 | LTB4R (0.37) | ERBB2KDM4EHPGDL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912562-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003505-A2 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |