Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 8/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575556 | 1.00 | PPARG (0.39) | PPARGCYP1A2PPARAPPARDNR4A2 | |
| SCHEMBL5759912 | 0.82 | FFAR1 (0.43) | ERBB2KDM4EMEN1HPGDKMT2A | |
| SCHEMBL5759910 | 0.82 | FFAR1 (0.43) | ERBB2KDM4EMEN1HPGDKMT2A | |
| SCHEMBL8575564 | 0.80 | ERBB2 (0.35) | ERBB2KDM4EMEN1HPGDKMT2A | |
| SCHEMBL5758996 | 0.79 | CYP4F2 (0.42) | KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL5758992 | 0.79 | CYP4F2 (0.42) | KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL5758262 | 0.77 | ERBB2 (0.39) | CYP1A2ERBB2EPHX2KDM4EMEN1 | |
| SCHEMBL5758259 | 0.77 | ERBB2 (0.39) | CYP1A2ERBB2EPHX2KDM4EMEN1 | |
| SCHEMBL5760787 | 0.73 | LTB4R (0.37) | PPARGPPARAERBB2KDM4EMEN1 | |
| SCHEMBL7959564 | 0.73 | LTB4R (0.37) | PPARGPPARAERBB2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912562-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003505-A2 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |