Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 3/20 | 0.41 |
| ▸ | CMA1 | P23946 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414050 | 0.80 | DRD2 (0.54) | MEN1RAB9AKMT2ATSHRNOTUM | |
| SCHEMBL17754236 | 0.79 | PLA2G7 (0.49) | HTTSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL11082167 | 0.74 | MAPT (0.50) | HTTSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL17875267 | 0.74 | PKM (0.64) | SMN1; SMN2MEN1RAB9AKMT2ATSHR | |
| SCHEMBL13189312 | 0.74 | PLA2G7 (0.52) | HTTSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL11089881 | 0.72 | RAB9A (0.50) | HTTSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL20928543 | 0.71 | PLA2G7 (0.50) | HTTSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL10813333 | 0.71 | MEN1 (0.46) | HTTSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL10814849 | 0.71 | MEN1 (0.46) | HTTSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL2191993 | 0.71 | HTT (0.51) | HTTSMN1; SMN2MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |