Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556928 | 0.86 | ALDH1A1 (0.39) | THRBMEN1HTTKMT2AMAPT | |
| 1-Bromobutane SCHEMBL11006961 | 0.86 | TSHR (0.35) | THRBTSHRALDH1A1ADRB2ADRB1 | |
| SCHEMBL31151133 | 0.84 | THRB (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL6151432 | 0.82 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL9579658 | 0.82 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL23356864 | 0.80 | TSHR (0.57) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL616138 | 0.80 | TSHR (0.57) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL274644 | 0.80 | TSHR (0.57) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL273578 | 0.80 | TSHR (0.57) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL15023631 | 0.80 | TSHR (0.57) | THRBMEN1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708150-A | Process for preparing transition metal complexes containing disubstituted cyclopentadienyl ligands | WITCO GMBH (DE) | 1998-01-13 | — | — | US | disclosed |