Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576984 | 0.89 | OPRM1 (0.35) | SMN1; SMN2OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL8578477 | 0.83 | MMP1 (0.35) | SMN1; SMN2OPRM1OPRD1OPRK1BRD4 | |
| SCHEMBL8578903 | 0.81 | OPRM1 (0.34) | SMN1; SMN2OPRM1OPRD1OPRK1BRD4 | |
| SCHEMBL8578564 | 0.80 | OPRM1 (0.33) | SMN1; SMN2OPRM1OPRD1OPRK1BRD4 | |
| SCHEMBL8577363 | 0.78 | MEN1 (0.34) | SMN1; SMN2OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL8575949 | 0.77 | KMT2A (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8579077 | 0.73 | KDM4E (0.39) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8576766 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2OPRM1OPRD1MEN1KMT2A | |
| SCHEMBL8575820 | 0.72 | ACACB (0.35) | SMN1; SMN2OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL5252341 | 0.72 | PIN1 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719310-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5610122-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |