Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 5/20 | 0.30 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.30 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578718 | 0.86 | L3MBTL1 (0.34) | MCL1ALDH1A1KMT2AGSTO1KCNJ6 | |
| SCHEMBL8578764 | 0.82 | MCL1 (0.46) | MCL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8575221 | 0.82 | CA12 (0.33) | — | |
| SCHEMBL8576255 | 0.82 | CA12 (0.44) | MCL1ALDH1A1 | |
| SCHEMBL8578495 | 0.71 | MCL1 (0.47) | MCL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8577707 | 0.70 | MCL1 (0.48) | MCL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8575183 | 0.69 | CA2 (0.44) | ALDH1A1 | |
| SCHEMBL8571412 | 0.69 | MCL1 (0.44) | MCL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30516181 | 0.68 | HMGB1 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL8574456 | 0.68 | GSTO1 (0.40) | MCL1ALDH1A1KMT2ALMNAGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |