Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993129 | 0.86 | HTR6 (0.38) | HTR6FABP4HDAC6HDAC1HDAC11 | |
| SCHEMBL6978338 | 0.85 | HTR6 (0.36) | HTR6FABP4HDAC6HDAC8 | |
| SCHEMBL27862253 | 0.80 | FABP4 (0.38) | HTR6FABP4HDAC6HDAC1HDAC11 | |
| SCHEMBL6993132 | 0.79 | FABP4 (0.35) | HTR6FABP4HDAC6HDAC1HDAC11 | |
| SCHEMBL8577109 | 0.77 | HTR6 (0.36) | HTR6 | |
| SCHEMBL818662 | 0.77 | PLA2G2A (0.42) | HTR6FABP4 | |
| SCHEMBL6978340 | 0.77 | PLA2G2A (0.41) | HTR6 | |
| SCHEMBL8575155 | 0.73 | HTR6 (0.33) | HTR6FABP4 | |
| SCHEMBL8575157 | 0.71 | HTR6 (0.34) | HTR6FABP4 | |
| SCHEMBL6983124 | 0.70 | PLA2G2A (0.40) | HTR6FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018464-A1 | SUBSTITUTED TRICYCLICS | ELI LILLY AND COMPANY (US) | 1998-05-07 | — | — | WO | disclosed |