Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL857765 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2APAF1ASAH1KMT2AMEN1 | |
| Phenazine SCHEMBL28881744 | 0.75 | SLC7A5 (0.58) | SMN1; SMN2APAF1KMT2AMEN1NPC1 | |
| Carbamic Acid SCHEMBL10888970 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2ASAH1KMT2AMEN1DNMT3A | |
| SCHEMBL11882632 | 0.72 | KMT2A (0.57) | SMN1; SMN2ASAH1KMT2AMEN1DNMT3A | |
| SCHEMBL828619 | 0.72 | KMT2A (0.57) | SMN1; SMN2ASAH1KMT2AMEN1DNMT3A | |
| SCHEMBL3078847 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2APAF1ASAH1KMT2AMEN1 | |
| Quinoline SCHEMBL4747553 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL16596879 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2APAF1ASAH1KMT2AMEN1 | |
| SCHEMBL11443588 | 0.71 | KMT2A (0.60) | SMN1; SMN2ASAH1KMT2AMEN1DNMT3A | |
| SCHEMBL250172 | 0.71 | HTT (0.66) | SMN1; SMN2ASAH1KMT2AMEN1DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521200-A | ANTICONVULSANTS AND TREATMENT OF ANXIETY | HO WINSTON (US) | 1996-05-28 | — | — | US | disclosed |