Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9068323 | 0.75 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL8577778 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL29262831 | 0.67 | PNMT (0.37) | PNMTNPC1RAB9A | |
| SCHEMBL27574872 | 0.66 | PNMT (0.50) | PNMTNPC1RAB9A | |
| SCHEMBL29843963 | 0.66 | PNMT (0.41) | PNMTNPC1RAB9A | |
| SCHEMBL22165985 | 0.66 | PNMT (0.41) | PNMTNPC1RAB9A | |
| SCHEMBL61027 | 0.66 | PNMT (0.49) | PNMTNPC1RAB9A | |
| SCHEMBL5981385 | 0.66 | PNMT (0.49) | PNMTNPC1RAB9A | |
| SCHEMBL6671922 | 0.66 | PNMT (0.49) | PNMTNPC1RAB9A | |
| SCHEMBL29843943 | 0.66 | PNMT (0.49) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830958-A | Polynuclear metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-03 | — | — | US | disclosed |