Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8577781 | 0.75 | PNMT (0.30) | PNMT | |
| Hydrochloric Acid SCHEMBL9068321 | 0.74 | BCHE (0.36) | — | |
| SCHEMBL7647630 | 0.68 | PNMT (0.43) | PNMT | |
| SCHEMBL7197595 | 0.67 | PNMT (0.44) | PNMT | |
| SCHEMBL7584997 | 0.67 | PNMT (0.41) | PNMT | |
| SCHEMBL7576872 | 0.67 | PNMT (0.41) | PNMT | |
| SCHEMBL7634815 | 0.66 | NPC1 (0.35) | PNMT | |
| Hydrochloric Acid SCHEMBL17836040 | 0.66 | PNMT (0.34) | PNMT | |
| SCHEMBL27555872 | 0.65 | PNMT (0.47) | PNMT | |
| SCHEMBL313686 | 0.65 | PNMT (0.60) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745607-A2 | Metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-12-04 | — | — | EP | claimed |