SCHEMBL86424

SCHEMBL86424

C=CC(=O)Oc1ccc2sc3ccc4ccccc4c3c(=O)c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.45
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
PTPN7 P35236 1/20 0.38
DUSP3 P51452 1/20 0.38
PTPN12 Q05209 1/20 0.38
PTPN22 Q9Y2R2 1/20 0.38
HPGD P15428 3/20 0.37
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
RAD52 P43351 1/20 0.36
F12 P00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30998139 0.86 MAPT (0.61) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL85778 0.86 MAPT (0.61) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL16708721 0.84 KDM4E (0.49) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL3790672 0.78 ALDH1A1 (0.50) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL31120514 0.78 ALDH1A1 (0.50) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL85937 0.76 NPC1 (0.45) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL2742604 0.75 MAOA (0.54) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL28027775 0.74 NPC1 (0.46) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL11994247 0.74 MAPT (0.59) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL15292034 0.74 ALDH1A1 (0.47) MAPTKDM4EALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 MAPT 2087/4885KDM4E 679/4885ALDH1A1 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.