SCHEMBL8577930

SCHEMBL8577930

O=C(NCC1CO1)N(CC1CO1)C(=O)NCC1CO1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
USP2 O75604 1/20 0.33
MTNR1A P48039 1/20 0.32
HPGD P15428 4/20 0.32
TP53 P04637 1/20 0.32
ALOX12 P18054 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
HTT P42858 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13115813 1.00 SMN1; SMN2 (0.33) SMN1; SMN2USP2MTNR1AHPGDTP53
SCHEMBL29083340 0.88 SMN1; SMN2 (0.33) SMN1; SMN2USP2MTNR1AHPGDTP53
SCHEMBL27274527 0.88 MTNR1A (0.31) MTNR1A
SCHEMBL15827370 0.87 LMNA (0.35) HTTLMNA
Methane SCHEMBL28524803 0.86 USP2 (0.32) SMN1; SMN2USP2MTNR1AHPGDTP53
SCHEMBL20217112 0.86 MTNR1A (0.33) MTNR1A
SCHEMBL16307154 0.86 LMNA (0.31) SMN1; SMN2MTNR1AHPGDKMT2ANPC1
SCHEMBL21095245 0.86 ALOX5 (0.45) HPGDHTTLMNA
SCHEMBL13985113 0.81 USP2 (0.31) SMN1; SMN2USP2MTNR1AHPGDTP53
SCHEMBL467319 0.78 HTT (0.32) SMN1; SMN2MTNR1AHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2813891-A2 Photoresist underlayer film-forming composition and pattern forming process Shin-Etsu Chemical Co., Ltd. (JP) 2014-12-17 EP disclosed
WO-2013090529-A1 NEAR-INFRARED ABSORBING FILM COMPOSITION FOR LITHOGRAPHIC APPLICATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-06-20 WO disclosed
EP-2602274-A1 EPOXY RESIN COMPOSITION HAVING MONOCYCLIC ALIPHATIC HYDROCARBON RING Nissan Chemical Industries, Ltd. (JP) 2013-06-12 EP disclosed
WO-2012067071-A1 POLYFUNCTIONAL EPOXY COMPOUND 日産化学工業株式会社 (JP) 2012-05-24 WO disclosed
WO-2007038802-A2 METHODS FOR PREPARING CORE-SHELL COMPOSITES HAVING CROSS-LINKED SHELLS AND CORE-SHELL COMPOSITES RESULTING THEREFROM ILYPSA, INC. (US) 2007-04-05 WO disclosed