Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6982195 | 0.96 | SIGMAR1 (0.45) | SIGMAR1CCR3 | |
| SCHEMBL6981070 | 0.94 | SIGMAR1 (0.41) | SIGMAR1MEN1KMT2A | |
| SCHEMBL6981079 | 0.86 | HRH3 (0.40) | SIGMAR1CCR3 | |
| Hydrochloric Acid SCHEMBL6982807 | 0.86 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2A | |
| SCHEMBL6981931 | 0.85 | HRH3 (0.39) | SIGMAR1CCR3 | |
| SCHEMBL6985090 | 0.84 | OPRM1 (0.36) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6984864 | 0.83 | OPRL1 (0.38) | SIGMAR1 | |
| SCHEMBL6983492 | 0.83 | CHRNA7 (0.40) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6985053 | 0.82 | SMN1; SMN2 (0.41) | SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6983999 | 0.81 | SMN1; SMN2 (0.41) | SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |