Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6979051 | 0.85 | LMNA (0.41) | DRD2SIGMAR1DRD4ALDH1A1MAPT | |
| SCHEMBL8578232 | 0.83 | SIGMAR1 (0.46) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6980233 | 0.82 | CHRNA7 (0.39) | CHRNA7DRD2SIGMAR1KCNH2DRD4 | |
| Hydrochloric Acid SCHEMBL6984760 | 0.81 | DRD2 (0.40) | DRD2SIGMAR1CYP2D6HTR7HTR1A | |
| Hydrochloric Acid SCHEMBL6985853 | 0.81 | DRD2 (0.40) | DRD2SIGMAR1CYP2D6HTR7HTR1A | |
| SCHEMBL6979708 | 0.81 | PRMT6 (0.43) | SIGMAR1KCNH2 | |
| SCHEMBL8573871 | 0.80 | LMNA (0.42) | ALDH1A1KDM4EL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL6981605 | 0.78 | MEN1 (0.41) | DRD2CYP2D6KCNH2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6985676 | 0.78 | SMN1; SMN2 (0.42) | SIGMAR1CYP2D6ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL6981674 | 0.78 | SIGMAR1 (0.38) | DRD2SIGMAR1DRD4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |