Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584112 | 0.86 | EPHX2 (0.41) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL8585297 | 0.84 | HDAC1 (0.44) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL8581846 | 0.82 | NR1D1 (0.51) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL8583157 | 0.78 | TBXAS1 (0.56) | KDM4ETBXAS1KMT2A | |
| SCHEMBL8541916 | 0.77 | TBXAS1 (0.55) | L3MBTL1TBXAS1 | |
| SCHEMBL8544227 | 0.74 | TBXAS1 (0.46) | L3MBTL1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL8543141 | 0.74 | TBXAS1 (0.46) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL8541450 | 0.71 | TRPM5 (0.41) | L3MBTL1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL8578689 | 0.71 | HPGD (0.44) | L3MBTL1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL13774769 | 0.69 | KMT2A (0.56) | L3MBTL1ALDH1A1LMNAHTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |