Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585297 | 0.87 | HDAC1 (0.44) | TBXAS1MEN1KMT2AKDM4E | |
| SCHEMBL8581846 | 0.84 | NR1D1 (0.51) | TBXAS1KDM4E | |
| SCHEMBL8583185 | 0.83 | TBXAS1 (0.62) | TBXAS1MEN1KMT2APTGDR2KDM4E | |
| SCHEMBL8578692 | 0.78 | L3MBTL1 (0.43) | TBXAS1KMT2AKDM4E | |
| SCHEMBL8584112 | 0.77 | EPHX2 (0.41) | TBXAS1MEN1KMT2AKDM4E | |
| SCHEMBL8537426 | 0.77 | TBXAS1 (0.76) | TBXAS1 | |
| SCHEMBL8583413 | 0.75 | TBXAS1 (0.52) | TBXAS1PTGDR2KDM4E | |
| SCHEMBL8538814 | 0.74 | TBXAS1 (0.63) | TBXAS1 | |
| SCHEMBL8583787 | 0.74 | TBXAS1 (0.58) | TBXAS1PTGDR2 | |
| SCHEMBL8538702 | 0.73 | TBXAS1 (0.64) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |