Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346665 | 0.75 | POLB (0.32) | ALDH1A1GAAHPGDPOLBCYP3A4 | |
| SCHEMBL1219524 | 0.71 | ACHE (0.39) | XDHGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL1219525 | 0.70 | ESR1 (0.41) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7113522 | 0.65 | NR1H2 (0.33) | NR1H2NR1H3 | |
| SCHEMBL536223 | 0.63 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDNR1H2NR1H3 | |
| Catechol SCHEMBL7655560 | 0.62 | MAPT (0.42) | XDHGABRA1GABRB2ALDH1A1GAA | |
| SCHEMBL7118374 | 0.62 | ALDH1A1 (0.35) | ALDH1A1NR1H2NR1H3 | |
| SCHEMBL323547 | 0.62 | XDH (0.54) | XDHGABRA1GABRB2ALDH1A1MEN1 | |
| SCHEMBL16477652 | 0.60 | NR1H2 (0.33) | CNR1NR1H2NR1H3 | |
| SCHEMBL5026171 | 0.60 | NR1H2 (0.30) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909301-A1 | BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS | Smith & Nephew plc (GB) | 1999-04-21 | — | — | EP | disclosed |
| WO-1997048782-A1 | BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS | SMITH & NEPHEW PLC (GB) | 1997-12-24 | — | — | WO | disclosed |