Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 17/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677958 | 0.88 | APP (0.38) | GRM5APPCA12CA1CA2 | |
| SCHEMBL8579921 | 0.81 | CYP1A1 (0.31) | — | |
| SCHEMBL8577931 | 0.81 | GRM5 (0.61) | GRM5APPFFAR1 | |
| SCHEMBL8581528 | 0.77 | APP (0.33) | APP | |
| SCHEMBL8911138 | 0.76 | GRM5 (0.56) | GRM5APP | |
| SCHEMBL8578937 | 0.73 | NPC1 (0.37) | GRM5FFAR1 | |
| SCHEMBL8677974 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL10669403 | 0.68 | GRM5 (0.62) | GRM5APPFFAR1 | |
| SCHEMBL2191154 | 0.67 | APP (0.63) | GRM5APPFFAR1CA12CA1 | |
| SCHEMBL328827 | 0.67 | MAPT (0.37) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705578-A | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-06 | — | — | US | claimed |
| US-5830958-A | Polynuclear metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| US-5705578-A | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-06 | — | — | US | disclosed |