SCHEMBL328827

SCHEMBL328827

N#Cc1[c]c2c(cc1)-c1ccccc1C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 1/20 0.35
MAOA P21397 2/20 0.34
ADRA2A P08913 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTR2B P41595 1/20 0.33
SRD5A2 P31213 1/20 0.33
BCHE P06276 1/20 0.32
CES1 P23141 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8677974 0.80 ALDH1A1 (0.39) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL8677958 0.79 APP (0.38) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL3192097 0.73 ALDH1A1 (0.48) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL18242620 0.73 ALDH1A1 (0.40) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL216980 0.73 ALDH1A1 (0.40) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL7176422 0.73 ALDH1A1 (0.40) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL9064843 0.73 ALDH1A1 (0.40) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL2478927 0.73 RAB9A (0.40) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL18243664 0.73 ALDH1A1 (0.40) MAPTHPGDSMN1; SMN2ALDH1A1NPC1
SCHEMBL246575 0.73 ALDH1A1 (0.40) MAPTHPGDSMN1; SMN2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8900725-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. 2014-12-02 US claimed
US-8865322-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US claimed
EP-2407501-B1 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO LTD (KR) 2013-09-11 EP claimed
EP-2407502-B1 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO LTD (KR) 2013-06-19 EP claimed
US-20120013246-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US claimed
US-20120013247-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US claimed
EP-2407501-A1 Dendrimer and organic light-emitting device using the same Samsung Mobile Display Co., Ltd. (KR) 2012-01-18 EP claimed
EP-2407502-A1 Dendrimer and organic light-emitting device using the same Samsung Mobile Display Co., Ltd. (KR) 2012-01-18 EP claimed
US-7927719-B2 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-04-19 US claimed
EP-1921082-B1 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO LTD (KR) 2010-04-14 EP claimed
EP-1921082-A1 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound Samsung SDI Co., Ltd. (KR) 2008-05-14 EP claimed
US-20080106188-A1 SILANYLAMINE-BASED COMPOUND, METHOD OF PREPARING THE SAME AND ORGANIC LIGHT EMITTING DEVICE INCLUDING ORGANIC LAYER COMPRISING THE SILANYLAMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-08 US claimed
US-9537104-B2 Condensed-cyclic compound and organic light-emitting diode including the condensed-cyclic compound SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-03 US disclosed
US-8900725-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. 2014-12-02 US disclosed
US-8865322-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US disclosed
US-20140077175-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE CONDENSED-CYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2014-03-20 US disclosed
US-7927719-B2 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-04-19 US disclosed
EP-1921082-B1 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO LTD (KR) 2010-04-14 EP disclosed
EP-1921082-A1 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound Samsung SDI Co., Ltd. (KR) 2008-05-14 EP disclosed
US-20080106188-A1 SILANYLAMINE-BASED COMPOUND, METHOD OF PREPARING THE SAME AND ORGANIC LIGHT EMITTING DEVICE INCLUDING ORGANIC LAYER COMPRISING THE SILANYLAMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080106188-A1 SILANYLAMINE-BASED COMPOUND, METHOD OF PREPARING THE SAME AND ORGANIC LIGHT EMITTING DEVICE INCLUDING ORGANIC LAYER COMPRISING THE SILANYLAMINE-BASED COMPOUND ICMT, SLC43A1, SLC7A5 MAPT 1029/4885HPGD 3330/4885SMN1; SMN2 3880/4885
US-20140077175-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE CONDENSED-CYCLIC COMPOUND CCNL2, CRY1, CCND2 MAPT 1213/4885HPGD 1550/4885SMN1; SMN2 4647/4885
US-20120013247-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CLTB, CD40LG, DYNLL2 MAPT 446/4885HPGD 3620/4885SMN1; SMN2 3793/4885
US-20120013246-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CLTB, CD40LG, DYNLL2 MAPT 446/4885HPGD 3620/4885SMN1; SMN2 3793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.