Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033625 | 0.87 | MAPT (0.43) | MAPTSMN1; SMN2L3MBTL1UNGMEN1 | |
| SCHEMBL9720583 | 0.85 | TDP1 (0.46) | MAPTSMN1; SMN2L3MBTL1UNGMEN1 | |
| SCHEMBL19889497 | 0.84 | ALDH1A1 (0.42) | MAPTSMN1; SMN2L3MBTL1UNGMEN1 | |
| SCHEMBL10389972 | 0.83 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL4667601 | 0.81 | ALDH1A1 (0.57) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4667605 | 0.81 | ALDH1A1 (0.57) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8581009 | 0.81 | L3MBTL1 (0.51) | MAPTSMN1; SMN2L3MBTL1UNGKMT2A | |
| SCHEMBL4895021 | 0.80 | EPHX2 (0.54) | MAPTSMN1; SMN2L3MBTL1UNGMEN1 | |
| SCHEMBL11465197 | 0.78 | MEN1 (0.49) | SMN1; SMN2UNGMEN1KMT2AALDH1A1 | |
| SCHEMBL6671053 | 0.77 | PRSS1 (0.52) | MAPTSMN1; SMN2L3MBTL1ATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |