Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15285714 | 0.84 | ALDH1A1 (0.41) | RXFP1KDM4EHSD17B10NAPRTALDH1A1 | |
| SCHEMBL29181923 | 0.83 | RXFP1 (0.39) | RXFP1KDM4EHSD17B10NAPRTALDH1A1 | |
| SCHEMBL7553080 | 0.76 | ALDH1A1 (0.38) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7828458 | 0.75 | HSD17B10 (0.50) | KDM4EHSD17B10NAPRTALDH1A1MEN1 | |
| SCHEMBL19729186 | 0.74 | LMNA (0.45) | RXFP1KDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL8578153 | 0.73 | ALDH1A1 (0.46) | KDM4EHSD17B10NAPRTALDH1A1MEN1 | |
| SCHEMBL607237 | 0.72 | CYP1A2 (0.48) | KDM4EALDH1A1CYP1A2CA1CA2 | |
| SCHEMBL4601967 | 0.71 | MEN1 (0.50) | KDM4EMEN1KMT2AMAPTPOLB | |
| SCHEMBL30777877 | 0.71 | MYC (0.56) | KDM4EHSD17B10NAPRTALDH1A1MEN1 | |
| SCHEMBL8578051 | 0.71 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011438-A1 | SYNTHESIS OF QUINAZOLINONE LIBRARIES AND DERIVATIVES THEREOF | TREGA BIOSCIENCES, INC. (US) | 1998-03-19 | — | — | WO | disclosed |
| WO-1997010221-A1 | SYNTHESIS OF QUINAZOLINONE LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-03-20 | — | — | WO | disclosed |