Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580713 | 0.84 | ALDH1A1 (0.42) | ALDH1A1GAATSHRLMNATDP1 | |
| SCHEMBL8582463 | 0.81 | CYP1A2 (0.48) | ALDH1A1GAAMEN1CYP1A2KMT2A | |
| SCHEMBL8992161 | 0.75 | ALDH1A1 (0.40) | ALDH1A1GAATSHRLMNATDP1 | |
| SCHEMBL9028884 | 0.75 | ALDH1A1 (0.40) | ALDH1A1GAATSHRLMNATDP1 | |
| SCHEMBL8580408 | 0.75 | CYP1A2 (0.41) | GAACYP1A2 | |
| SCHEMBL9029562 | 0.74 | ALDH1A1 (0.40) | ALDH1A1GAATSHRLMNATDP1 | |
| SCHEMBL8585372 | 0.74 | CYP1A2 (0.45) | ALDH1A1GAAMEN1CYP1A2KMT2A | |
| SCHEMBL8933379 | 0.74 | ALDH1A1 (0.40) | ALDH1A1GAATSHRLMNATDP1 | |
| SCHEMBL8910093 | 0.72 | LMNA (0.37) | ALDH1A1GAATSHRLMNATDP1 | |
| SCHEMBL8583985 | 0.71 | CYP1A2 (0.47) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731336-A | USING ARYL-SUBSTITUTED RHODAMINES | ELI LILLY AND COMPANY (US) | 1998-03-24 | — | — | US | disclosed |