Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582463 | 0.74 | CYP1A2 (0.48) | ALDH1A1GAAMEN1KMT2AALOX5 | |
| SCHEMBL8992157 | 0.73 | SMN1; SMN2 (0.36) | LMNAALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL8992154 | 0.73 | SMN1; SMN2 (0.36) | LMNAALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL8933377 | 0.72 | SMN1; SMN2 (0.37) | LMNAALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL8933375 | 0.72 | SMN1; SMN2 (0.37) | LMNAALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL8580683 | 0.72 | ALDH1A1 (0.40) | LMNAALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL8580408 | 0.68 | CYP1A2 (0.41) | GAAALOX5PTGS1PTGS2 | |
| SCHEMBL8908613 | 0.68 | PTGS2 (0.41) | LMNAGAASMN1; SMN2NPSR1RECQL | |
| SCHEMBL8991924 | 0.67 | MEN1 (0.40) | LMNAALDH1A1GAASMN1; SMN2NPSR1 | |
| SCHEMBL8895686 | 0.67 | MEN1 (0.40) | LMNAALDH1A1GAASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691367-A | ANTIINFLAMMATORY AGENTS OR ANTIARTHRITIC AGENTS | ELI LILLY AND COMPANY (US) | 1997-11-25 | — | — | US | disclosed |