Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582631 | 0.99 | YAP1 (0.41) | YAP1SLC9A1OPRK1KDM4EMEN1 | |
| SCHEMBL8585395 | 0.95 | SLC9A1 (0.39) | YAP1SLC9A1OPRK1CA1CA2 | |
| SCHEMBL8580663 | 0.90 | SCN9A (0.38) | YAP1SLC9A1OPRK1CA1CA2 | |
| SCHEMBL8584027 | 0.85 | SLC9A1 (0.48) | YAP1SLC9A1KDM4E | |
| SCHEMBL8582854 | 0.84 | KDM4E (0.40) | YAP1SLC9A1KDM4EMEN1MAPT | |
| SCHEMBL8581253 | 0.84 | SLC9A1 (0.47) | YAP1SLC9A1KDM4EMAPT | |
| SCHEMBL8581988 | 0.84 | SCN9A (0.42) | SLC9A1 | |
| SCHEMBL8585515 | 0.83 | SCN9A (0.43) | YAP1SLC9A1 | |
| SCHEMBL8580817 | 0.83 | ALDH1A1 (0.42) | YAP1SLC9A1KDM4EMEN1MAPT | |
| SCHEMBL8583683 | 0.83 | SLC9A1 (0.40) | YAP1SLC9A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |