Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585395 | 0.95 | SLC9A1 (0.39) | SCN9AALDH1A1HPGDHSD17B10OPRK1 | |
| SCHEMBL8580822 | 0.90 | YAP1 (0.39) | OPRK1SLC9A1KDM4ECA1CA2 | |
| SCHEMBL8582631 | 0.89 | YAP1 (0.41) | ALDH1A1OPRK1SLC9A1KDM4EKMT2A | |
| SCHEMBL8585228 | 0.85 | SCN9A (0.40) | SCN9AALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8583881 | 0.85 | ALDH1A1 (0.47) | SCN9AALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8581975 | 0.84 | SCN9A (0.39) | SCN9AALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8579383 | 0.81 | SCN9A (0.37) | SCN9AALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8582805 | 0.81 | OPRK1 (0.35) | ALDH1A1OPRK1KDM4ECA1CA2 | |
| SCHEMBL8584023 | 0.80 | SLC9A1 (0.50) | HSD17B10SLC9A1KDM4EPDK2PDK4 | |
| SCHEMBL8585506 | 0.80 | SCN9A (0.37) | SCN9AALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |