Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583100 | 0.87 | FFAR4 (0.38) | ALDH1A1HSD17B10HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL8578771 | 0.86 | TAS1R3 (0.37) | ALDH1A1HSD17B10TSHRHPGDKDM4E | |
| SCHEMBL8583191 | 0.86 | KDM4E (0.36) | ALDH1A1HSD17B10TSHRHPGDKDM4E | |
| SCHEMBL8582996 | 0.84 | KDM4E (0.37) | ALDH1A1HSD17B10TSHRHPGDKDM4E | |
| SCHEMBL27367149 | 0.83 | TAS1R3 (0.32) | TAS1R3TAS1R1TAS1R2LMNAHTT | |
| SCHEMBL8581355 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KDM4ESMN1; SMN2KMT2AYAP1 | |
| SCHEMBL8581200 | 0.83 | ALOX5AP (0.37) | ALDH1A1HSD17B10TSHRHPGDKDM4E | |
| SCHEMBL8579296 | 0.82 | PDK2 (0.39) | ALDH1A1HSD17B10TSHRHPGDKDM4E | |
| SCHEMBL8578782 | 0.82 | DRD2 (0.38) | ALDH1A1HSD17B10TSHRHPGDKDM4E | |
| SCHEMBL8580134 | 0.81 | YAP1 (0.39) | ALDH1A1HSD17B10TSHRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |