Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | HTR1F | P30939 | 5/20 | 0.56 |
| ▸ | HCN1 | O60741 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 5/20 | 0.43 |
| ▸ | HTR1D | P28221 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583475 | 0.88 | HTR1A (0.46) | HTR1AHTR1FHCN1HDAC3HDAC4 | |
| SCHEMBL8587381 | 0.88 | HTR1A (0.56) | HTR1AHTR1FHDAC3HDAC4HDAC1 | |
| SCHEMBL8584386 | 0.87 | SMN1; SMN2 (0.48) | HTR1AHTR1FHDAC3HDAC4HDAC1 | |
| SCHEMBL8585944 | 0.86 | HTR1F (0.42) | HTR1AHTR1FHDAC3HDAC4HDAC1 | |
| SCHEMBL8584947 | 0.85 | HTR1A (0.58) | HTR1AHTR1FHCN1HTR1BTP53 | |
| SCHEMBL8586359 | 0.84 | HTR1F (0.53) | HTR1AHTR1FHDAC3HDAC4HDAC1 | |
| SCHEMBL8584888 | 0.82 | ALDH1A1 (0.48) | HTR1AHTR1FHTR1BHTR1DKMT2A | |
| SCHEMBL8586100 | 0.81 | HTR1D (0.41) | HTR1AHTR1FPOLBHTR1BHTR1D | |
| SCHEMBL8585018 | 0.79 | HTR1D (0.40) | HTR1AHTR1FHDAC3HDAC4HDAC1 | |
| SCHEMBL8636423 | 0.78 | HTR1F (0.54) | HTR1AHTR1FHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |