Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.69 |
| ▸ | AOC2 | O75106 | 2/20 | 0.69 |
| ▸ | MAOA | P21397 | 2/20 | 0.69 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585084 | 1.00 | MAOB (0.69) | MAOBAOC2MAOAAOC3PTPN1 | |
| SCHEMBL7322216 | 0.83 | MAOB (0.71) | MAOBAOC2MAOAAOC3FFAR1 | |
| SCHEMBL7322207 | 0.83 | MAOB (0.71) | MAOBAOC2MAOAAOC3FFAR1 | |
| Mofegiline SCHEMBL1295041 | 0.81 | MAOB (1.00) | MAOBAOC2MAOAAOC3FFAR1 | |
| Mofegiline SCHEMBL14005358 | 0.81 | MAOB (1.00) | MAOBAOC2MAOAAOC3FFAR1 | |
| Mofegiline SCHEMBL147813 | 0.81 | MAOB (1.00) | MAOBAOC2MAOAAOC3FFAR1 | |
| SCHEMBL8585905 | 0.81 | AOC2 (0.69) | MAOBAOC2MAOAAOC3FFAR1 | |
| Mofegiline SCHEMBL1295043 | 0.81 | MAOB (1.00) | MAOBAOC2MAOAAOC3FFAR1 | |
| SCHEMBL8585907 | 0.81 | AOC2 (0.69) | MAOBAOC2MAOAAOC3FFAR1 | |
| SCHEMBL14005455 | 0.81 | AOC3 (0.69) | MAOBAOC2MAOAAOC3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875499-A2 | Process for the crystallisation of alkali metal salts of diformylamide | HOECHST MARION ROUSSEL, INC. (US) | 1998-11-04 | — | — | EP | claimed |
| US-5488188-A | Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-01-30 | — | — | US | claimed |
| EP-0875499-A2 | Process for the crystallisation of alkali metal salts of diformylamide | HOECHST MARION ROUSSEL, INC. (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5679854-A | Process for the preparation of (epsilon)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane and novel intermediate thereof | HOECHST MARION ROUSSEL, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5599986-A | CRYSTALLIZATION YIELDS PURE FREE-FLOWING GRANULAR SOLIDS | HOECHST MARION ROUSSEL INC. (US) | 1997-02-04 | — | — | US | disclosed |
| US-5488188-A | Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-01-30 | — | — | US | disclosed |