Mofegiline

Mofegiline

SCHEMBL14005358

NC/C(=C/[18F])CCc1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 1.00
AOC2 O75106 5/20 1.00
MAOA P21397 5/20 1.00
AOC3 Q16853 2/20 1.00
DAO P14920 2/20 0.57
TAAR1 Q96RJ0 3/20 0.50
LOXL2 Q9Y4K0 1/20 0.43
FFAR1 O14842 1/20 0.41
SLC5A1 P13866 1/20 0.39
SLC5A2 P31639 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mofegiline SCHEMBL147813 1.00 MAOB (1.00) MAOBAOC2MAOAAOC3DAO
Mofegiline SCHEMBL1295041 1.00 MAOB (1.00) MAOBAOC2MAOAAOC3DAO
Mofegiline SCHEMBL1295043 1.00 MAOB (1.00) MAOBAOC2MAOAAOC3DAO
Mofegiline SCHEMBL343685 0.98 MAOB (0.96) MAOBAOC2MAOAAOC3DAO
Mofegiline SCHEMBL125286 0.98 MAOB (0.96) MAOBAOC2MAOAAOC3DAO
Mofegiline SCHEMBL343686 0.98 MAOB (0.96) MAOBAOC2MAOAAOC3DAO
SCHEMBL1295016 0.84 MAOB (0.72) MAOBAOC2MAOAAOC3DAO
SCHEMBL1295522 0.84 MAOB (0.72) MAOBAOC2MAOAAOC3DAO
SCHEMBL1294767 0.84 MAOB (0.72) MAOBAOC2MAOAAOC3DAO
SCHEMBL1295015 0.84 MAOB (0.72) MAOBAOC2MAOAAOC3DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080292547-A1 Novel Imaging Agents for Fibrosis TOLLESHAUG HELGE 2008-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080292547-A1 Novel Imaging Agents for Fibrosis LOXL1, LOXL2, LOXL3 MAOB 703/4885AOC2 468/4885MAOA 1033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.