Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 6/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581606 | 0.92 | GHSR (0.42) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8612146 | 0.88 | GHSR (0.42) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8584100 | 0.88 | GHSR (0.42) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8997596 | 0.85 | GHSR (0.35) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8613152 | 0.84 | GHSR (0.36) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8997591 | 0.84 | GHSR (0.36) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8583595 | 0.80 | GHSR (0.44) | GHSRLMNACXCR5MTNR1AMTNR1B | |
| SCHEMBL8582293 | 0.79 | SYK (0.44) | GHSR | |
| SCHEMBL8579256 | 0.79 | GHSR (0.44) | GHSRCXCR5MTNR1AMTNR1BKDM1A | |
| SCHEMBL1162409 | 0.78 | GHSR (0.48) | GHSRCXCR5HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |