Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 7/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579256 | 0.87 | GHSR (0.44) | GHSRRPS6KA1CXCR5KDM1ADPP8 | |
| SCHEMBL8997625 | 0.84 | GHSR (0.37) | GHSRRPS6KA1KDM1ADPP8DPP9 | |
| SCHEMBL8581093 | 0.84 | GHSR (0.40) | GHSRRPS6KA1NAMPT | |
| SCHEMBL8580646 | 0.82 | GHSR (0.42) | GHSRCXCR5LMNASMN1; SMN2 | |
| SCHEMBL8845267 | 0.81 | GHSR (0.42) | GHSRCXCR5 | |
| SCHEMBL8845155 | 0.81 | GHSR (0.42) | GHSRCXCR5 | |
| SCHEMBL8845103 | 0.81 | GHSR (0.41) | GHSRCXCR5 | |
| SCHEMBL8585491 | 0.80 | GHSR (0.42) | GHSRCXCR5KDM1ALMNAMTNR1A | |
| SCHEMBL8614342 | 0.80 | GHSR (0.40) | GHSRCXCR5KDM1A | |
| SCHEMBL8581652 | 0.78 | GHSR (0.48) | GHSRCXCR5BACE1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |